Genetic Testing Underused for GI Cancers (Lynch Syndrome vs. BRCA) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Tuesday, February 09, 2016

Genetic Testing Underused for GI Cancers (Lynch Syndrome vs. BRCA)



Clinical Oncology News (requires login to view - free)

 Although Lynch syndrome is almost as prevalent as hereditary breast and ovarian cancer (HBOC), twice as many patients are undergoing testing for breast and ovarian cancer as for GI cancer syndromes, according to a recent study presented at the 2015 annual meeting of the American College of Gastroenterology (abstract P159)......

 Observing that there were few referrals for GI cancers during the interim analysis of this study, the researchers set out to quantify the extent of the problem. In an analysis of 500 patients, almost twice as many patients received genetic testing for a primary workup of HBOC as for a workup of GI cancer syndromes (66.4% vs. 28.8%). Although newly diagnosed colorectal and gastric cancer constituted 42% of the approximately 1,798 new diagnoses of all breast, ovarian, colorectal and GI cancers at the three centers, only 29% of the tests were ordered for GI indications.

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