The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer

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 Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer

 Introduction

• The New FIGO Classification
• Stage I
• Stage II
• Stage III
• Stage IV
• The New WHO Classification
• Serous tumors
• Mucinous tumors
• Seromucinous tumors
• Endometrioid tumors
• Clear cell tumors
• Brenner tumors
• References

sample excerpt:
 Clear cell tumors
The new WHO classification has not resulted in any significant changes in the classification of clear cell tumors. Clear cell BOTs are very similar to clear cell adenomas and parts of both entities are usually present in tumors. In contrast, clear cell carcinomas are irregular, with papillary structures, solid parts with desmoplastic hyalinized stroma, and high-grade nuclear atypia [22]. Clear cell carcinomas may be associated with Lynch syndrome but also with endometriosis and are the most common ovarian carcinoma with paraneoplastic symptoms (thromboembolism and hypercalcemia) [24], [25].