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open access:
Systematic Review of Monitoring Criteria to Interpret CA125 Increments during First-Line Chemotherapy and the Subsequent Follow-Up Period among Patients with Advanced Epithelial Ovarian Cancer - systematic-review-of-monitoring-criteria-to-interpret-ca125-increments-during-firstline-chemotherapy-and-the-subsequent-followup-period-among-patients-with-advanced-epithelial-ovarian-cancer-jcop-1000101.pdf
Conclusion:
Consistent criteria for indicating disease progression with CA125 could not be defined due to differences in trial design and selection of patients. The most promising criteria should be re-evaluated under similar and standardized conditions. Computer simulation models and change point algorithms may aid in identifying CA125 assessment criteria to be further validated in prospective clinica
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